临床药学与药理学系讲师

金红兰-简介

发布日期:2020年09月03日   阅读人数:

金红兰,药学博士、延边大学药学院讲师、硕士研究生导师。 主要从事眼科疾病和肿瘤的表观遗传调控机制研究,主持国家自然科学基金项目及延边大大学博士启动基金项目,以第一作者和通讯发表SCI文章10余篇。主要讲授课程为《药理学研究进展》、《药物毒理学》、《药剂学实验》、《工业药剂学实验》等。

【联系方式

邮箱: honglanjin@ybu.edu.cn

电话:04332436577

【教育经历】

2014/03-2017/08,韩国嘉泉大学,药理学,博士

2010/09-2013/08,延边大学,生药学,硕士

2006/09-2010/08,延边大学,药学,学士

【工作经历】

2018-至今,延边大学,药学院,讲师

2017-2018,韩国亚洲大学,生命科学,博士后

【研究领域】

组蛋白修饰在基因表达调控中的作用及其分子机理研究;

基于多组学数据及生物信息学研究,筛选疾病靶点并阐明其作用机制

【科研项目】

1.国家自然科学基金地区科学基金项目(2020.01-2023.12),主持

2.延边大学博士启动基金项目(2020.07-2023.07),主持

【代表论著】

1.Chung Young Sun, Jin Hong Lan*, Jeong Kwang Won*, Cell type-specific expression of ENACα gene by FOXA1 in the glucocorticoid receptor pathway, International Journal of Immunopathology and Pharmacology, 2020,

2. Hong Lan Jin, Se-Young Choung*, Kwang Won Jeong*, Protective mechanisms of polyphenol-enriched fraction of Vaccinium uliginosum L. Against blue light-induced cell death of human retinal pigmented epithelial cells, Journal of Functional Foods, 2017, 39: 28-36.

3. Hong Lan Jin, Yujin Choi, Kwang Won Jeong*, Crosstalk between Aryl Hydrocarbon Receptor and Glucocorticoid Receptor in Human Retinal Pigment Epithelial Cells, International journal of endocrinology, 2017, 2017:1-9.

4. Hong Lan Jin, Liu Yang, and Kwang Won Jeong. "Flightless-I homolog regulates glucocorticoid receptor-mediated transcription via direct interaction of the leucine-rich repeat domain." Molecular Biology Reports, 44.2 (2017): 243-250.

5. Hong Lan Jin, Kwang Won Jeong*, Regulation of aryl hydrocarbon receptor-mediated transcription in human retinal pigmented epithelial cells, Biochemical and biophysical research communications, 2016, 472: 366-372.

6. Hong Lan Jin, Sung-Chan Lee, Yong Sam Kwon, Se-Young Choung*, Kwang Won Jeong*, A novel fluorescence-based assay for measuring A2E removal from human retinal pigment epithelial cells to screen for age-related macular degeneration inhibitors, Journal of pharmaceutical and biomedical analysis, 2016, 117: 560-567.

7. Jun Kim (Co-1st) #, Hong Lan Jin (Co-1st)#, Dae Sik Jang, Kwang Won Jeong*, Se-Young Choung*, Hyperoside (quercetin-3-O-β-D-galactopyranoside) protects A2E-laden retinal pigmented epithelium cells against UVA and blue light-induced apoptosis in vitro and in vivo, Journal of Functional Foods, 2018, 40: 426-437.

8. Jun Kim(Co-1st)#, Hong Lan Jin(Co-1st)#, Kwang Won Jeong and Se-Young Choung. "Quercetin-3-O-α-L-arabinopyranoside protects against retinal cell death via blue light-induced damage in human RPE cells and Balb-c mice." Food & Function, 2018, 9, 2171-2183.

9. Zhe Wang, MY Li, ZH Zhang, HX Zuo, JY Wang, Y Xing, MH Ri, Hong Lan Jin, CH Jin, GH Xu, LX Piao, CG Jiang*, Juan Ma,*, Xuejun Jin*, Panaxadiol inhibits programmed cell death-ligand 1 expression and tumour proliferation via hypoxia-inducible factor (HIF)-1α and STAT3 in human colon cancer cells, Pharmacological Research., 2020, 155, 104727.

10. Ming Li Jin1, Young Woong Kim1, Hong Lan Jin1, Hoin Kang2, Eun Kyung Lee2, Michael R. Stallcup3*, Kwang Won Jeong1*. "Aberrant expression of SETD1A promotes survival and migration of estrogen receptor α-positive breast cancer cells." International journal of cancer, 2018, 143(11):2871-2883.

【授权专利】

1. Kwang Won Jeong, Hong Lan Jin, Se-Young Choung, Nam-Joon Baek, Yong Sam Kwon, A2E-BDP and screening method of inhibitors of intracellular A2E accumulation or removers of intracellular A2E removal using the same, 2015, 韩国, 10-2015-0131337.

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